Two sample MR report
ELP5_Conventional Dendritic Cell against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 0.0406862 | 0.2223374 | 0.8599909 |
| Weighted median | 9 | 0.0393459 | 0.0105386 | 0.0001888 |
| Inverse variance weighted | 9 | 0.0400439 | 0.0084045 | 0.0000019 |
| Simple mode | 9 | 0.0389471 | 0.0153458 | 0.0348213 |
| Weighted mode | 9 | 0.0387286 | 0.0157536 | 0.0394174 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4278799 | 7 | 0.9996701 |
| Inverse variance weighted | 0.4278882 | 8 | 0.9999264 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0004372 | 0.1512164 | 0.997774 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001562 | 0 | TRUE | 0.2375099 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
